Buy Aricept Online

What is Aricept?

Aricept improves the function of nerve cells in the brain. It works by preventing the breakdown of a chemical called acetylcholine (ah see til KO leen). People with dementia usually have lower levels of this chemical, which is important for the processes of memory, thinking, and reasoning.

Aricept is used to treat mild to moderate dementia caused by Alzheimer's disease.

Aricept may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Aricept?

Before taking Aricept, tell your doctor if you have a heart rhythm disorder such as "sick sinus syndrome" (slow heartbeats), an enlarged prostate, urination problems, asthma, obstructive pulmonary disease, or a seizure disorder such as epilepsy.

If you need to have any type of surgery, tell the surgeon ahead of time that you are taking Aricept.

Aricept can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

What should I discuss with my healthcare provider before taking Aricept?

Do not take Aricept if you are allergic to donepezil.

Before taking Aricept, tell your doctor if you are allergic to any drugs, or if you have:

  • a heart rhythm disorder such as "sick sinus syndrome" (slow heartbeats);

  • a history of stomach ulcers;

  • an enlarged prostate or urination problems;

  • epilepsy or other seizure disorder; or

  • asthma or chronic obstructive pulmonary disease (COPD).

If you have any of these conditions, you may need a dose adjustment or special tests to safely take Aricept.

FDA pregnancy category C. Aricept may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether Aricept passes into breast milk or if it could harm a nursing baby. Do not use Aricept without telling your doctor if you are breast-feeding a baby.

How should I take Aricept?

Take Aricept exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

If you need to have any type of surgery, tell the surgeon ahead of time that you are taking Aricept. You may need to stop using the medicine for a short time.

Aricept can be taken with or without food or milk.

Take the Aricept regular tablets with a full glass of water.

To take donepezil orally disintegrating tablet (Aricept ODT):

  • Keep the tablet in its blister pack until you are ready to take the medicine. Open the package and peel or cut the backing from the tablet blister. Do not push a tablet through the backing or you may damage the tablet.

  • Using dry hands, remove the tablet and place it in your mouth. It will begin to dissolve right away.

  • Do not swallow the tablet whole. Allow it to dissolve in your mouth without chewing.

  • Swallow several times as the tablet dissolves. After the tablet dissolves completely, drink a glass of water.

Aricept is usually taken at bedtime. Follow your doctor's instructions. Store Aricept at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include severe nausea, vomiting, drooling, sweating, blurred vision, feeling light-headed, slow heartbeat, shallow breathing, muscle weakness, fainting, or seizure (convulsions).

What should I avoid while taking Aricept?

Aricept can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Aricept side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using Aricept and call your doctor at once if you have any of these serious side effects:
  • black, bloody, or tarry stools;

  • coughing up blood or vomit that looks like blood or coffee grounds;

  • painful or difficult urination;

  • seizure (black-out or convulsions);

Less serious side effects may include:

  • nausea, vomiting, diarrhea;

  • loss of appetite;

  • muscle cramps;

  • tired feeling; or

  • sleep problems (insomnia).

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Aricept?

Before taking Aricept, tell your doctor if you are taking any of the following medicines:

  • atropine (Donnatal, and others);

  • belladonna;

  • carbamazepine (Tegretol);

  • clidinium (Quarzan);

  • dexamethasone (Decadron);

  • dicyclomine (Bentyl);

  • glycopyrrolate (Robinul);

  • hyoscyamine (Anaspaz, Cystospaz, Levsin, and others);

  • mepenzolate (Cantil);

  • methantheline (Provocholine);

  • methscopolamine (Pamine), scopolamine (Transderm-Scop);

  • phenobarbital (Luminal, Solfoton);

  • phenytoin (Dilantin);

  • propantheline (Pro-Banthine);

  • quinidine (Cardioquin, Quinidex, Quinaglute, others);

  • rifampin (Rifadin, Rifamate, Rifater);

  • a fungal antibiotic such as ketoconazole (Nizoral), fluconazole (Diflucan), or itraconazole (Sporanox); or

  • aspirin or other NSAIDs (non-steroidal anti-inflammatory drugs) such as ibuprofen (Motrin, Advil), naproxen (Aleve, Naprosyn), diclofenac (Voltaren), diflunisal (Dolobid), etodolac (Lodine), flurbiprofen (Ansaid), indomethacin (Indocin), ketoprofen (Orudis), ketorolac (Toradol), mefenamic acid (Ponstel), meloxicam (Mobic), nabumetone (Relafen), piroxicam (Feldene), and others.

This list is not complete and there may be other drugs that can interact with Aricept. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

For the Consumer

Applies to donepezil: oral tablet, oral tablet disintegrating

Along with its needed effects, donepezil (the active ingredient contained in Aricept) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur while taking donepezil:

More common
  • Diarrhea
  • loss of appetite
  • muscle cramps
  • nausea
  • trouble in sleeping
  • unusual tiredness or weakness
  • vomiting
Less common
  • Abnormal dreams
  • constipation
  • dizziness
  • drowsiness
  • fainting
  • frequent urination
  • headache
  • joint pain, stiffness, or swelling
  • mental depression
  • pain
  • unusual bleeding or bruising
  • weight loss
Rare
  • Black, tarry stools
  • bloating
  • bloody or cloudy urine
  • blurred vision
  • burning, prickling, or tingling sensations
  • cataract
  • chills
  • clumsiness or unsteadiness
  • confusion
  • cough
  • decreased urination
  • difficult or painful urination
  • dryness of mouth
  • eye irritation
  • fever
  • flushing of skin
  • frequent urge to urinate
  • high or low blood pressure
  • hives
  • hot flashes
  • increase in sexual desire or performance
  • increased heart rate and breathing
  • increased sweating
  • increased urge to urinate during the night
  • irregular heartbeat
  • itching
  • loss of bladder control
  • loss of bowel control
  • mood or mental changes, including abnormal crying, aggression, agitation, delusions, irritability, nervousness, or restlessness
  • nasal congestion
  • pain in chest, upper stomach, or throat
  • problems with speech
  • runny nose
  • severe thirst
  • shortness of breath
  • sneezing
  • sore throat
  • sunken eyes
  • tightness in chest
  • tremor
  • troubled breathing
  • wheezing
  • wrinkled skin
Incidence not known
  • Back, leg, or stomach pains
  • bleeding gums
  • chest pain or discomfort
  • coma
  • convulsions
  • dark urine
  • difficulty breathing
  • fast or irregular heartbeat
  • fatigue
  • general body swelling
  • general tiredness and weakness
  • high fever
  • increased thirst
  • indigestion
  • light-colored stools
  • muscle pain or cramps
  • nausea and vomiting
  • nosebleeds
  • pains in stomach, side, or abdomen, possibly radiating to the back
  • pale skin
  • rash
  • seeing, hearing, or feeling things that are not there
  • seizures
  • severe muscle stiffness
  • severe nausea
  • slow or irregular heartbeat
  • stomach pain
  • sweating
  • swelling of face, ankles, or hands
  • tiredness
  • unusually pale skin
  • upper right abdominal or stomach pain
  • yellow eyes and skin
Symptoms of overdose
  • Convulsions (seizures)
  • increased sweating
  • increased watering of mouth
  • increasing muscle weakness
  • low blood pressure
  • severe nausea
  • severe vomiting
  • slow heartbeat
  • troubled breathing

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Applies to donepezil: oral tablet, oral tablet disintegrating

Nervous system

The case of restless legs, mumbling, and stuttering resolved after discontinuation of donepezil (the active ingredient contained in Aricept) and there was a positive rechallenge.

Nervous system side effects have included headache (10%), insomnia (up to 9%), dizziness (up to 8%), hostility (3%), nervousness (3%), hallucinations (3%), somnolence (2%), depression (2%), confusion (2%), emotional lability (2%), and personality disorder (2%). Delusions, tremor, irritability, paresthesia, aggression, vertigo, ataxia, increased libido, restlessness, abnormal crying, and aphasia have been reported frequently. Cerebrovascular accident, intracranial hemorrhage, transient ischemic attack, neuralgia, coldness (localized), muscle spasm, dysphoria, gait abnormality, hypertonia, hypokinesia, neurodermatitis, numbness (localized), paranoia, dysarthria, dysphasia, decreased libido, melancholia, emotional withdrawal, nystagmus, and pacing have been reported infrequently. A case of Pisa Syndrome and a dose-related case of restless legs, mumbling, and stuttering have been reported. Two cases of worsening Parkinson's disease, a case report of convulsions, and a case report of delirium which may possibly have been associated with the use of donepezil have also been reported.

Genitourinary

Genitourinary side effects including incontinence (7%) have been reported. Nocturia has been reported frequently. Dysuria, hematuria, urinary urgency, metrorrhagia, cystitis, enuresis, prostate hypertrophy, pyelonephritis, inability to empty bladder, breast fibroadenosis, fibrocystic breast, mastitis, pyuria, renal failure, and vaginitis have been reported infrequently.

Musculoskeletal

Musculoskeletal side effects including muscle cramps (6%) and back pain (3%) have been reported. Bone fracture has been reported frequently. Muscle weakness, and muscle fasciculation have been reported infrequently.

Gastrointestinal

Gastrointestinal side effects reported in at least 5% of patients include nausea, vomiting, diarrhea, and anorexia. Fecal incontinence, gastrointestinal bleeding, bloating, and epigastric pain have been reported frequently. Eructation, gingivitis, increased appetite, flatulence, periodontal abscess, cholelithiasis, diverticulitis, drooling, dry mouth, fever sore, gastritis, irritable colon, tongue edema, epigastric distress, gastroenteritis, increased transaminases, hemorrhoids, ileus, increased thirst, jaundice, melena, polydipsia, duodenal ulcer, and stomach ulcer have been reported infrequently.

Dermatologic

Dermatologic side effects including eczema (3%) have been reported. Pruritus, diaphoresis, and urticaria have been reported frequently. Dermatitis, erythema, skin discoloration, hyperkeratosis, alopecia, fungal dermatitis, herpes zoster, hirsutism, skin striae, night sweats, and skin ulcer have been reported infrequently. A case of purpuric rash has been reported.

Cardiovascular

Cardiovascular side effects including hypertension (up to 3%), hemorrhage (up to 2%), and syncope (2%) have been reported. Hypotension and bradycardia have been reported in less than 1% of patients. Vasodilation, atrial fibrillation, hot flashes, and hypotension have been reported frequently. Angina pectoris, postural hypotension, myocardial infarction, AV block (first degree), congestive heart failure, arteritis, bradycardia, peripheral vascular disease, supraventricular tachycardia, and deep vein thrombosis have been reported infrequently.

Metabolic

Metabolic side effects have included dehydration (2%), hyperlipemia (2%), and weight loss with increasing dosage. Gout, hypokalemia, increased creatine kinase, hyperglycemia, increased weight, and increased lactate dehydrogenase have been reported infrequently.

General

Frequency of common adverse effects may be influenced by the rate of titration.

General side effects including fever (2%) and chest pain (2%) have been reported. Fever, facial edema, periorbital edema, hiatal hernia, abscess, cellulitis, chills, generalized coldness, head fullness, and listlessness have been reported infrequently. Side effects are generally mild in nature and well tolerated.

Other

Other side effects including earache, tinnitus, decreased hearing, otitis externa, otitis media, bad taste, ear buzzing, and motion sickness have been reported infrequently. Cholinergic effects such as frequent urination have been reported in 2% of patients. Tremor, restlessness, hypertension, hypotension, ataxia, bradycardia, and diaphoresis have been reported in less than 1% of patients.

Ocular

Ocular side effects including cataract, eye irritation, and blurred vision have been reported frequently. Dry eyes, glaucoma, blepharitis, retinal hemorrhage, conjunctival hemorrhage, and spots before eyes have been reported infrequently.

Endocrine

Endocrine side effects including diabetes mellitus and goiter have been reported infrequently.

Hematologic

Hematologic side effects including anemia, thrombocythemia, thrombocytopenia, eosinophilia, and erythrocytopenia have been reported infrequently.

Respiratory

Respiratory side effects including dyspnea, sore throat, and bronchitis have been reported frequently. Epistaxis, post nasal drip, pneumonia, hyperventilation, pulmonary congestion, wheezing, hypoxia, pharyngitis, pleurisy, pulmonary collapse, sleep apnea, and snoring have been reported infrequently.

Psychiatric

Psychiatric side effects including nightmares have been reported.